 Idebenone is a cerebral stimulant that increases brain energy levels and has a rejuvenating effect on the whole body
Idebenone is a synthetic analogue of coenzyme Q10 (CoQ10), the vital cell membrane antioxidant and essential constituent of the ATP-producing mitochondrial electron transport chain (ETC). Idebenone is a potent antioxidant, with the ability to operate under low oxygen tension situations.
Because of its ability to inhibit lipid peroxidation, Idebenone protects cell membranes and mitochondria from oxidative damage. Its antioxidant properties protect against cerebral ischemia and nerve damage in the central nervous system. Idebenone also interacts with the ETC, preserving ATP formation in ischemic states. This compound has also been shown to stimulate nerve growth factor, a characteristic that could be important in the treatment of Alzheimer's and other neurodegenerative diseases.
Idebenone is a potent cerebral stimulant that can increase brain energy. Like CoQ10, Idebenone protects the heart and is a powerful antioxidant. Idebenone also enhances brain levels of serotonin and norepinephrine, and increases brain levels of nerve growth factor; effects that have not been demonstrated with CoQ10.
CoQ10 is an important antioxidant component of the lipid (fatty) membranes that surround all cells, as well as the lipid membranes surrounding the various organelles, such as mitochondria and microsomes, inside cells.
CoQ10 is also an important member of the Electron Transport Chain (ETC) within mitochondria, the power plants contained in every cell. Most of the oxygen we breathe is used inside the ETC to produce much of the ATP bioenergy that powers virtually every activity of our cells and bodies.
Without CoQ10, or a good substitute, human life quickly ends. Idebenone may be a better CoQ10 that has been extensively researched for over 15 years.
When blood flow is seriously reduced to any part of the body (due to heart attack, stroke, trauma, shock, or chronic poor blood circulation) cellular and mitochondrial oxygen levels quickly drop in the affected region. Yet because O2 is seven-to-eight times more soluble in the lipid zones of cell membranes, compared to the watery compartments of the cell, there is still sufficient O2 remaining in the membranes of cells and organelles, as well as in the ETC, to auto-oxidize CoQ10. As the CoQ10 auto-oxidizes, hydrogen peroxide, superoxide and hydroxl free radicals are rapidly formed in massive numbers. These free radicals quickly damage cell/ organelle structure and function, as well as rapidly halt ATP energy generation by the ETC.
Brain and spinal cord cells are especially prone to such damage, and may be irreparably damaged or even destroyed within minutes.
Studies have shown that under the same cellular low oxygen conditions that cause CoQ10 to act as a pro-oxidant producer of damaging free radicals, Idebenone prevents the free radical damage and maintains relatively normal cell ATP levels. In short, while Idebenone can effectively substitute for CoQ10s positive and life- essential functions, it doesn't have CoQ10s free radical-producing and energy-crashing dark side which can occur under hypoxic conditions.
A variety of studies using brain cells (animal and humans) have shown Idebenone's ability to enhance brain structure and function. Human and animal studies have demonstrated that Idebenone can enhance serotonin production, even under far less than optimal conditions, as e.g. with a very low tryptophan diet, or in patients with cerebrovascular dementia.
Idebenone has enhanced cholinergic nerve function and consequent learning ability even under hypoxic conditions, or when an anti-cholinergic drug (Scopolamine) was administered. Idebenone has increased cellular catecholamine (dopamine, adrenaline and noradrenanlin) production by enhancing cellular uptake of the precursor amino acid tyrosine.
Idebenone enhances long-term potentiation in hippocampal nerve cells, a key part of memory formation and consolidation. Idebenone has restored glucose utilization and ATP production in ischemic rat-brain.
Idebenone has been shown to enhance general cerebral metabolism, lessen the damage from strokes, and has been used to treat Alzheimer's.
Like the original nootropic drug, Piracetam, Idebenone has been shown to promote information transfer across the corpus-callosum, the membrane separating the right and left brain hemispheres.
Idebenone also protects other organs in many ways. It cushions them against hypoxic and/ or ischemic damage. Idebenone enhances both normal and hypoxic ATP energy generation. Each cell in our organs must produce the energy it needs for life and health. Cells cannot borrow energy from each other.
Idebenone is a powerful antioxidant. Even more so than CoQ10. In some studies, Idebenone was 30 to 100 times more effective than vitamin E or Vinpocetine as a free radical quencher within brain cells.
Idebenone lessens the free radical-induced mtDNA damage that accumulates, accelerating over a lifetime, slowing organ damage and aging.
Therefore, with all these powers, Idebenone should now rightfully take its place in the first rank of anti-aging/ nootropic/ energizer drugs, along with Hydergine, Piracetam, Vinpocetine, Acetyl-L-carnitine, Deprenyl and GH3. It is the ideal choice for people who desire cognitive enhancement and brain energizer effects (it synergizes well with Piracetam, Vinpocetine and Hydergine).
Dosage: 1 tablet 2 or 3 times daily.
Safety: There are no known contraindications or side-effects.
Disclaimer: This product and its statements have not been evaluated by the FDA. This product is not intended to treat, cure or prevent any disease. The above information is provided under the supplying company's terms and conditions and should not replace the advice of your personal physician.
Restrictions: This product is not available for shipment to the UK
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