Safety
Amantadine may enhance the adverse effects of antimuscarinics and the dose of these drugs should be reduced when used with Amantadine. If combined with the classic Parkinson's drug Sinemet, then the adverse effects of L-dopa may be exacerbated. It is also recommended that Amantadine should be used with caution if combined with drugs with CNS stimulant properties, particularly those that may enhance dopamine. Furthermore, the rate of excretion of Amantadine may be reduced by drugs that raise urinary pH.
Persons taking prescription medication and pregnant or lactating women should consult a physician before using this product. Long-term use of this product should be supervised and monitored by a health care professional.