 Metformin regulates blood glucose levels to tackle age-related diabetes and lower cholesterol
Our brand of Metformin - Metforal is also known as Glucophage, or Dianben, has been described by Ward Dean MD, as one of the most important anti-aging drugs available today.
Metformin is used by diabetics to increase the body's receptor sensitivity to insulin. This is important for anti-aging, because we all lose insulin sensitivity with advancing age, (particularly past the age of 40). In fact, it is considered that we all become diabetic with age, because of the continual loss of the insulin/ glucose sensitivity.
Metformin is also known to lower cholesterol levels and helps prevent low-density lipoproteins, (LDL/ bad cholesterol) from attaching to blood platelets and arteries, thereby reducing the risk of blood clotting.
Furthermore, due to the sugar stabilizing properties of Metformin, it is also a useful aid for dieters, helping to prevent sugar cravings and therefore maintain a diet plan.
Metformin was used recently as an "antidote" to weight gain induced by several different medications. It was remarkably effective in a small, uncontrolled (no placebo group) study -- meaning that these results should be interpreted with caution. Fifteen of the 19 patients lost weight, and some who continued Metformin lost 10-30 pounds.
Metformin is a medication given for the treatment of diabetes. Sometimes it is used for people who only have "insulin resistance". In this condition, people have difficulty responding to their own insulin. As a result, the body releases even more insulin trying to make up for this problem. However, insulin has many effects around the body.
One of these insulin effects may change a person's "metabolism" in very profound ways. Excess insulin can induce something called "metabolic syndrome". In younger women, this is sometimes recognized through infertility, or growing excess hair, and in that setting is called "Polycystic Ovarian Syndrome" (PCOS). Not everyone who has insulin resistance gets PCOS or metabolic syndrome, or diabetes – but many do.
Metformin can decrease this "insulin resistance". It can restore fertility. It can decrease excess hair growth and other body changes. In some cases this medication can decrease abdominal obesity, or at least assist people in their efforts to control their weight. In some people it can suppress appetite somewhat. It is now being tested for use with medications that commonly increase appetite and weight.
B-12 Deficiency: Between 10 and 30% of people taking Metformin have a decrease in their B12 levels. B-12 is a vitamin required for production of red blood cells, so if you're low, one of the ways this can show up is "anaemia" -- too few red blood cells. The cells you do make actually come out too big in this situation, so it's pretty easy to recognize this problem. A simple blood test will easily reveal this anaemia and identify B-12 deficiency as a likely culprit.
Because Metformin can inhibit the uptake of vitamin B12, so a B12 supplement is recommend whilst using Metformin.
Metformin may be synergistic with Acarbose and Aminoguanidine.
Dosage: Regular doses for those over 40 years of age are just one tablet, (500mg each) once, twice or three times a day. Consult your physician if you are a diabetic, have any liver or kidney problems or have ever suffered from lactic acidosis, before use. Stop use if you feel unwell.
Safety: You should stop this medication if you have surgery, and begin taking it again when you are eating normal foods. Do not allow a contrast agent for a radiology procedure (e.g. a kidney test called an IVP) to be given while you are taking this medication; discuss how to handle any need for that test with your doctor.
Finally, some reports, but not all, caution against use of Metformin along with certain medications that are handled by the kidney, called "cationic drugs". You should review your other medications with your doctor and pharmacist regarding this issue. Lithium is actually such a cation, but there are no clear reports of problems with lithium and Metformin together.
Store in a dry place. Keep out of the reach of children.
Persons taking prescription medication and pregnant or lactating women should consult a physician before using this product. Long-term use of this product should be supervised and monitored by a health care professional.
Disclaimer: This product and its statements have not been evaluated by the FDA. This product is not intended to treat, cure or prevent any disease. The above information is provided under the supplying company's terms and conditions and should not replace the advice of your personal physician.
Restrictions: This product is not available for shipment to the EU
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