Desmopressin (Minirin®)
(US) $24.99


Future proof your memory with Desmopressin

In an ever changing world, we’re increasingly bombarded with new information. Recalling key facts, figures, names and faces is an important part of our busy lives, and memory enhancement supplements are something many are turning towards as an aide to better recollection. Memory supplements such as Desmopressin can help improve your memory and have a beneficial effect on your work and social life. Imagine never forgetting a business contact or important details in conversations at work, home or study.

Desmopressin is an effective memory enhancement supplement

Desmopressin is a man – made form of vasopressin -a 9 amino acid peptide hormone that occurs naturally in the brain of each and every one of us. Sometimes referred to as arginine vasopressin (AVP), argipressin or, more commonly, anti – diuretic hormone (ADH), vasopressin has a number of far reaching benefits for the mind, body and regulating systems of our daily bodily functions. One such specific benefit is the implication of vasopressin in helping to improve your memory by assisting our minds to form and store memories.

Alternative and previously developed memory supplements, such as Lyprseein and Pitressin are commonly made from animal sources. Desmopressin is synthetic and possesses more potency as a form of vasopressin and therefore has increased memory enhancement properties than other supplements on the market.

What is the role of Vasopressin in our bodies?

One of vasopressin’s functions is to regulate how much water the body retains. The retention is especially important in relation to our salt levels, an essential balancing act known as homeostasis; the name given to the body’s regulation of its inner environment. When we become dehydrated, vasopressin is released, causing our kidneys to conserve water, then our urine becomes concentrated and the frequency in which we need to urinate is lessened and the volume of water passed, reduced.

Vasopressin also acts as a vasoconstrictor -causing the muscular walls of blood vessels to contract when we are, for example, cold. This makes the walls narrower, raising our blood pressure and also constricting capillaries, determining where blood would flow to be most effective for your body to retain heat and regulate temperature efficiently.

Not only is Vasopressin essential to this regulation, it also has been found to affect the way in which we form and store memories. Because Desmopressin affects the brain, it belongs to a class of netraceuticals called Nootropics. This category of supplements work to improve your memory, facilitate faster cognitive function and act as a memory enhancement. Nootropics are also defined as drugs that are neuroprotective, non-toxic, and posses few side effects. Desmopressin is one such memory supplement that enables these positive effects.

What are the effects of Desmopressin as a Nootropic?

The majority of the body’s supply of vasopressin is stored in the posterior pituary, one of the lobes of the pituitary gland – a pea sized gland located at the base of the brain. When vasopressin is released, not only does it have an effect on our body’s regulatory impulses, it also has a direct impact on a part of the brain called the Hippocampus.

Located deep within the forebrain, the Hippocampus forms part of the Limbic system. This limbic system being a set of brain structures that are involved in a variety of differing functions -shaping emotion, behaviour, olfaction (the sense of smell) and memory.

By specifically having an effect on the Hippocampus – where new memories are formed, processed and transferred – Desmopressin is potent as a memory enhancement supplement, working to improve your memory and form lasting memories at the specific time when memories are being formed. Unlike taking another memory supplement, which may help our capacity to remember past events more effectively than without any supplement, Desmopressin helps us form lasting memories immediately; in effect, future proofing our memories by improving our ability to ‘file’ information as it happens, then retain and recall quickly and efficiently, right on cue.

How does Desmopressin work?

Not only does Desmopressin reduce the amount of water via urine our bodies expel, but vitally, it’s a very effective memory supplement -increasing the amount of synthetic vasopressin in your system means that you’ll be able to improve your memory from the moment you begin to use the supplement. Desmopressin works almost instantly via a nasal spray, permeating the nasal membrane which, of course, lies very close to the brain. This means that within about 15 minutes, the full benefits of the memory enhancement supplement will be felt.

Ideally Desmopressin should be taken just before study, meetings or any other event that requires significant concentration. The effects are marked and well documented – it’s the only Nootropic to future proof your memory.


Using the nasal spray, simply insert one or two sprays into the nose before it is required. Each spray delivers a dose of 5 mcg.

If you are familiar with earlier animal sourced vasopressins such as Lypressin and Pitressin, please be aware that Desmopressin (which now replaces these earlier forms of vasopressins) is much more potent. It is degraded more slowly and therefore requires less frequent administration.


As with all medications, Desmopressin should be used in accordance with instructions and should be treated with respect. Any warnings should be heeded carefully. In particular:

  • Desmopressin should not be used permanently, unless under medical supervision.
  • Desmopressin must not be used before heavy exercise
  • Desmopressin must not be used before drinking alcohol or lots of fluids
  • It is also important to avoid swallowing water whilst swimming if you have taken Desmopressin
  • Desmopressin should be avoided completely if you suffer from cardiovascular problems

The reason that there is particular reference above to fluid intake, including swallowing water whilst swimming, is due to the fact that Desmopressin in combination with excessive fluid consumption can result in hyponatremia, an imbalance between intracellular and extracellular sodium. This imbalance is a serious condition that can lead to seizures, brain swelling, and, in extreme cases, death. Therefore, if you do experience an unusually bad or prolonged headache, confusion, nausea, or vomiting whilst using Desmopressin contact your doctor or the nearest hospital casualty department immediately before taking another dose. If you do accidentally overdose you should also contact your doctor or nearest hospital emergency room straight away.

Side effects

Most people find that using Desmopressin causes them no problems at all and they do not suffer from any side effects. Occasionally some people suffer from headache, stomach ache, nausea, blocked or runny nose or nose bleeds.

An allergic reaction to the preservative such as skin rash, itching or sore nose can occur rarely.

If you are unfortunate enough to experience one or more of these side effects or any other undesirable effects, you should inform your health care professional.

Desmopressin will help you stop forgetting

Desmopressin improves the brain’s ‘filing mechanism’, allowing memories to be recalled quickly and easily

Desmopressin is the synthetic version of vasopressin, a peptide hormone found naturally in the brain and partly responsible for ‘inserting’ memories in the hippocampus, the region of the brain where memories are stored.

Desmopressin rapidly improves short-term memory and enhances memory imprinting. Desmopressin is sometimes used for the treatment of diabetes insipidus, a condition of frequent urination and extreme thirst. In some countries, Desmopressin is used for amnesia and to treat narcotic-related mental problems.

Whereas many common memory drugs improve the capability to remember past events easier and faster, Desmopressin helps us to remember future events better! That is, taking Desmopressin before an event, firmly imprints the event in the mind, enabling it to be recalled with more detail later. Consequently, Desmopressin is of particular benefit before lectures, business meetings and other such occasions.


Insert one or two sprays into each nostril (each spray contains 10mcg) 15 minutes before recall or concentration is required. The effect can take place within seconds and last for up to several hours.

Side effects:

Nausea and headaches


Desmopressin should be used infrequently. It should be avoided completely if you suffer from cardiovascular problems. Avoid the intake of large amounts of liquids as Desmopressin tends to decrease the frequency of urination.

Please note:

Vasopressin (also known as Diapid®) is of bovine and porcine origin, and has now been withdrawn from the world market. Desmopressin is more potent than Vasopressin and should be used in lower doses. Also, Desmopressin affects other brain receptor sites to a greater degree than the Vasopressin version.


Desmopressin should be kept in a fridge although it is stable for several weeks at room temperature.

Frequently Asked Questions About Desmopressin

Disclaimer: Please note that only your own physician can determine your precise needs, but in order to give you some information these answers are based upon the ‘average person’ and clinical / published results.

How many sprays are there in a bottle of desmopressin?

Currently in each 2.5ml bottle of Minurin® there is a total of 125 mcg of desmopressin. Each spray releases 5 mcg which means there are 25 sprays in total.